Paolo Zunino
Assistant Professor in Numerical Analysis
Contacts
Dipartimento di Matematica (
MOX )
Politecnico di Milano (Polimi
)
Piazza L. Da Vinci 32
Milano, ITALY
e-mail :
paolo.zunino@polimi.it
tel : +39 02 2399 4530
fax : +39 02 2399 4606 |

... believe it or not, I really look like this!
|
Education
Awards
Publications (
Books,
Refereed Journals,
Proceedings)
International Conferences and Invited Seminars
Teaching Activities
Work Experience and Collaborations
Links
Recipient of the SIAM
Outstanding Paper Prize
(see also the SIAM
official website and the Abstract
of this paper)
Curriculum Vitae
English extended version, PDF file (download with Shift+mouse click)
Italian short version, PDF file (download with Shift+mouse click)
Education
November 2002 - April 2005: Post. Doc. Institute of Analysis and
Scientific Computing, CMCS, EPFL
October 2002:Ph.D. in Applied Mathematics, EPFL
Subject of the Thesis: Mathematical and Numerical Modelling of Mass Transfer in the Vascular System.
Download Thesis.
Advisor: Prof. A. Quarteroni.
April 1999: Degree in Aerospace Engineering,
Politecnico di Milano.
Subject of the Bachelor Thesis: Mass transport through permeable membranes in emodynamics.
Advisor: Prof. A. Quarteroni; Co-Advisor: Dr. A. Veneziani.
Awards
Awarded with the SIAM Outstanding Paper Prize by the Society for Industrial and Applied
Mathematics, on July 2004 in Portland, Oregon, for the paper A Domain Decomposition
Method for Advection-Diffusion Processes with Application to Blood Solutes, by Alfio Quarteroni, Alessandro Veneziani and Paolo
Zunino, appeared in the SIAM Journal on Scientific Computing in 2002.
The prizes, first awarded in 1999, are given for outstanding papers published in SIAM journals during the three
years prior to the year of the award. The selection committee for this year's award consisted of Walter Strauss (Chair), Jerrold
Griggs, and Thomas Y. Hou.
For more information, see the
SIAM
website
Publications
Books:
- K.Perktold, M.Prosi, P.Zunino,
Mathematical models of mass transfer in the vascular walls, Chapter 7 of
Cardiovascular Mathematics, Springer Series on Modeling, Simulation and Applications,
L.Formaggia, A.Quarteroni, A.Veneziani (Eds.), Springer-Verlag, Berlin Heidelberg, 2009, ISBN: 978-88-470-1151-9
(link)
- S.Salsa, F.Vegni, A.Zaretti, P.Zunino,
Invito alle Equazioni a Derivate Parziali,
UNITEXT, Springer Italia, Milano, 2009, ISBN: 978-88-470-1179-3
(link)
Articles on Refereed Journals:
Subject classification: Mathematics (indexed AMS - Mathscinet)
- L. Formaggia, S. Minisini, P. Zunino, Modeling erosion controlled drug release and
transport phenomena in the arterial tissue, to appear on Math. Mod. Meth. Appl. Sci. (M3AS), 2010
- C.D'Angelo, P.Zunino,
A finite element method based on weighted interior penalties for heterogeneous incompressible flows,
SIAM J. Numer. Anal., Vol. 47, No. 5, pp. 3990-4020 (2009)
- P.Zunino, Numerical approximation of incompressible flows
with net flux defective boundary conditions by means of penalty techniques,
Comput. Methods Appl. Mech. Engrg. Vol. 198 (2009), No. 37-40, pp. 3026-3038
- P.Zunino, C.D'Angelo, L.Petrini, C.Vergara, C.Capelli, F.Migliavacca,
Numerical simulation of drug eluting coronary stents: mechanics, fluid dynamics and drug release,
Comput. Methods Appl. Mech. Engrg. Vol. 198 (2009), No. 45-46,
pp. 3633-3644, special issue on Models and Methods in Computational Vascular
and Cardiovascular Mechanics.
- P.Zunino, Discontinuous Galerkin methods based on weighted interior penalties
for second order PDEs with non-smooth coefficients , J. Sci. Comput.
Vol. 38, No 1, (2009), pp. 99-126.
- C. Vergara, P. Zunino, Multiscale boundary conditions for drug release from cardiovascular stents ,
SIAM Multiscale Model. Simul. Vol. 7, No. 2 (2008), pp. 565-588.
- A. Ern, A. Stephansen, P. Zunino, A Discontinuous Galerkin method with weighted averages for advection-diffusion equations
with locally vanishing and anisotropic diffusivity, IMA J. Numer. Anal. Vol. 29, No. 2 (2009)
- E. Burman, P. Zunino, A domain decomposition method based on weightd interior penalties
for advection-diffusion-reaction problems, SIAM J. Numer. Anal. Vol. 44 (2006), No. 4, pp. 1612-1638.
- F.Calabr\`o, P.Zunino, Analysis of parabolic problems on partitioned domains with nonlinear conditions at the interface.
Application to mass transfer through semi-permeable membranes., Math. Mod. Meth. Appl. Sci. (M3AS)
Vol. 16, No. 4 (2006), pp. 479-501.
- A. Quarteroni, A. Veneziani, P. Zunino,
Domain Decomposition Methods for Blood Solute Dynamics,
SIAM J. Sci. Comput., Vol. 23 (2002), No. 6, pp. 1959-1980.
- A. Quarteroni, A. Veneziani, P. Zunino,
Mathematical and Numerical Modelling of Solute Dynamics in Blood Flow and Arterial Walls,
SIAM J. Numer. Anal., Vol 39 (2002), No. 2, pp. 1488-1511.
- L. Formaggia, S.Perotto and P. Zunino, An Anisotropic a-posteriori
error estimate for a convection-diffusion problem,Comput. Visual. Sci.
Vol. 4 (2001), No. 2, pp. 105-109.
Subject classification: Life Sciences (indexed MEDLINE - Pubmed)
- Joao S. Soares, Paolo Zunino,
A mixture model for water uptake, degradation, erosion and drug release from polydisperse polymeric networks,
Biomaterials, In Press, Corrected Proof, Available online 2 February 2010, ISSN 0142-9612, DOI: 10.1016/j.biomaterials.2010.01.008.
- F.Migliavacca, F.Gervaso, M.Prosi, P.Zunino, S.Minisini, L.Formaggia and G.Dubini,
Expansion and drug elution model of a coronary stent, Comput. Methods. Biomech. Biomed. Engin.
Vol. 10, No. 1 (2007), pp. 63-73.
(indexed MEDLINE, journal home page)
- Antonio F. Corno, Martin Prosi, Pierre Fridez, Paolo Zunino, Alfio
Quarteroni, Ludwig K. von Segesser The non-circular shape of FloWatch(r)-PAB
prevents the need for pulmonary artery reconstruction after banding. Computational
fluid dynamics and clinical correlations Eur. J. Cardiothorac. Surg. 2006 Jan;29(1):93-9. Epub 2005 Dec 6.
(indexed MEDLINE, journal home page)
- M. Prosi, P.Zunino, K. Perktold, A. Quarteroni, Mathematical and numerical models for transfer of
low density lipoproteins through the arterial walls: a new methodology for
the model set up with applications to the study of disturbed lumenal flow, J. of Biomech., vol 38, (2005)
pp. 903-917. (indexed MEDLINE, journal home page)
- P. Zunino Multidimensional pharmacokinetic models applied to the design of drug eluting
stents, Cardiovasc. Eng., Vol. 4, No. 2 (2004), pp. 181-191.
(indexed MEDLINE, journal home page)
Conference Proceedings (with peer review)
Subject classification: Mathematics (indexed AMS - Matscinet)
- C. D'Angelo, P. Zunino, Multiscale models of drug delivery by thin implantable devices
to appear on Applied and industrial mathematics in Italy III,
Series on Advances in Mathematics for Applied Sciences, World Sci. Publ.
Vol. 75, 2009, pp. 597--608.
- P. Zunino, Energy norm a-posteriori error estimates
for a discontinuous Galerkin scheme applied to elliptic problems with an interface,
to appear on the Procceedings of the International Conference on
Boundary and Interior Layers - Computational & Asymptotic Methods (BAIL2008),
Lecture Notes in Computational Science and Engineering, Springer.
- P. Zunino, An adaptive discontinuous Galerkin scheme for second order problems with an interface,
Numerical Mathematics and Advanced Applications, Springer, Proceedings of ENUMATH 2007,
the 7th European Conference on Numerical Mathematics and Advanced Applications, Graz, Austria, September 2007, pp. 209--216.
- C. D'Angelo, P. Zunino, Numerical simulation of the interaction between blood flow and drug release from stents,
Numerical Mathematics and Advanced Applications, Springer, Proceedings of ENUMATH 2007,
the 7th European Conference on Numerical Mathematics and Advanced Applications, Graz, Austria, September 2007, pp. 157--164.
- P. Zunino, Mortar and discontinuous Galerkin methods based on weighted interior penalties,
Domain Decomposition Methods in Science and Engineering XVII, Austria, July 3-7 2006,
Lecture Notes in Computational Science and Engineering
Vol 60, 2007, Langer, U.; Discacciati, M.; Keyes, D.; Widlund, O.; Zulehner, W. (Eds.), Springer, ISBN: 978-3-540-75198-4
- P. Zunino, Iterative substructuring methods for advection-diffusion problems in heterogeneous media,
Challenges in Scientific Computing CISC2002, (Proceedings of
CISC2002 Conference, Berlin, 2002), Series: Lecture Notes in Computational Science and
Engineering, E. Baensch Ed., 2003 VIII, ISBN 3-540-40887-8, Springer, pp.184-210.
Conference Proceedings (without peer review)
- M. Prosi, F. Gervaso, P. Zunino, S. Minisini and L. Formaggia.
Numerical simulation of drug release from stents.
Computer Methods in Biomechanics and Biomedical Engineering - CMBBE 2006.
Eds. Middleton J, Shrive NG and Evans S, FIRST Numerics Ltd., Cardiff (UK)
- D.Mastalli, A.Quarteroni, P.Zunino A steepest descent algorithm for control problems with switches.
Application to the optimization of peritoneal dialysis. Proceedings of the
Fourth International Workshop on Scientific Computing and Applications, June 20-23 2005, Shanghai, China,
Science Press of China, 2005, pp. 50-62.
- P. Zunino, D.Mastalli, Optimal control of peritoneal dialysis.
Proceedings of the conference: Control Systems: Theory, Numerics and Applications, Rome, 30 March - 1 April 2005
on Procedings of Science, S.I.S.S.A.
- D.Mastalli, A.Quarteroni, P.Zunino, Modelli matematici per l'ottimizzazione della dialisi peritoneale
Istituto Lombardo Accademia di Scienze e Lettere, Collezione delle Lezioni del Ciclo
Scienze e tecnologie per lo sviluppo sostenibile della societ\`a umana, anno 2002/2003, 13 pagine.
- L.Formaggia, F.Nobile, A.Quarteroni, A.Veneziani, P.Zunino, Advances on Numerical Modelling of Blood Flow Problems,
Proceedings of ECCOMAS 2000 Conference, E. Onate Ed., CDROM, ISBN 84-89925-70-4.
- A.Quarteroni, A.Veneziani, P.Zunino, Numerical investigation of transport and absorption phenomena of blood solutes, in the 18th National Heat Transfer Conference, A. Niro et al. Eds. ETIS, Pisa, 2000, pp.955-966.
Technical notes:
- P.Zunino, D.Mastalli, A.Quarteroni, F.Neftel, J.P.Wauters, Development of a new mathematical approach to optimize
peritoneal dialysis, S\'erie d'Analyse et Analyse Num\'erique, Departement de Mathematiques, EPFL, No.11, 2004.
Participation to International Conferences and Invited Seminars
March 2009: SIAM Conference on Computational Science and Engineering (CSE09), Miami, USA.
- Title: The interaction of blood flow and drug release for cardiovascular drug eluting stents.
Numerical treatment of net flux boundary conditions.
August 2008: Boundary and Interior Layers Computational & Asymptotic Methods (BAIL2008), Limerick, Ireland.
- Title: Discontinuous Galerkin methods based on weighted interior penalties for second order problems with interfaces
July 2008: 8th World Congress on Computational Mechanics, Venice, Italy
- Minisymposium: Biofluids and Coupled Problems in Biomechanics.
Title: The interaction of blood flow and drug release for cardiovascular drug eluting stents.
- Minisymposium: Theory and Applications of Discontinuous Galerkin Methods.
Title: A posteriori error estimates for Discontinuous Galerkin methods based on weighted interior penalties.
May 2008: Workshop on Optimal Transport in the Human Body: Lungs and Blood. IPAM-UCLA, Los Angeles, USA.
- Title: Mathematical and numerical modelling of drug release in the vascular system
September 2007: ENUMATH 2007, Graz, Austria
- Title: Discontinuous Galerkin methods based on weighted interior penalties
- Minisymposium on Mathematical Modeling in Medicine.
Title: Mathematical models and numerical simulation of drug release from stents.
July 2007: 9th US National Congress on Computational Mechanics (USNCCM9), San Francisco, USA
- Title: Mathematical models and numerical simulation of drug release from stents
February 2007: Workshop on Variational Multiscale Methods and Stabilized Finite Elements (VMS07), EPFL, Lausanne
- Title: Weighted Interior Penalties for Mortar and Discontinuous Galerkin Methods
July 2006: 17th International Conference on Domain Decomposition Methods, St. Wolfang, Austria
- Title: Domain decomposition methods based on weighted interior penalties
December 2005 INRIA, Paris, France, CEA-EDF-INRIA School: Numerical simulation of blood flows.
- Title: Mathematical modelling and simulation of biochemical transport
November 2005: 3rd European Medical & Biological Engineering Conference (EMBEC'05), Prague
- Title: Mathematical modelling of mass trandfer in the vascular system
June 2005: The 3rd Finite Element Fair, Universita' Degli Studi, Pavia
- Title: Weighted interior penalty methods for non-negative partial differential equations
April 2005: Workshop "Numerics and Control", Rome, Istituto Nazionale di Alta Matamatica (INDAM)
- Title: Optimal Control of Peritoneal Dialysis
November 2003: INSA, Laboratoire CREATIS, Lyon.
- Title: Mathematical and numerical models for mass transfer aimed to
the characterization of the physical properties of the arterial walls.
September 2003: Computational Modelling in Medicine, JMCB
University of Edinburgh.
- Title: Mathematical modeling of mass transfer in the vascular system and related clinical applications.
July 2003: 15th International Conference on Domain Decomposition Methods, Berlin.
- Title:Iterative substructuring methods for advection-diffusion problems in heterogeneous media.
June 2003: Workshop on Cardiovascular, Respiratory and Metabolic Control Modelling, University of Graz, Austria.
- Title: Mathematical and numerical modelling of mass transfer in the vascular system and related clinical applications.
October 2002: Challenges In Scientific Computing Conference, Weierstrass Institut, Berlin.
- Title: Mathematical and numerical modelling of mass transfer in the vascular system.
July 2002: 5th ESMTB Conference on Mathematical Modelling and Computing in Biology and Medicine, Milan.
- Title: Modelling and simulation of solute dynamics in the vascular system.
March 2002: Workshop: Cardiovascular System-from Mathematical Modeling to Clinical Applications,
Politecnico di Milano, Milan
- Title: Mathematical and numerical modeling of solute dynamics in blood flow and arterial walls.
May 2001: Technical University Graz.
- Title: Modeling of macromolecule transport in arterial walls: existence of a solution.
October 2000: AMIF International Conference on Applied Mathematics for Industrial Flow Problems, Il Ciocco, Italy.
- Title: Multifield Models for Bio-engineering Applications.
Poster Sessions:
- A. Corno, V. Milisic, P. Zunino, A. Quarteroni.,
Computational/mathematical modeling of the systemic and pulmonary circulations with and without ventricular septal defect.,
42nd Annual Meeting of the Association for European Paediatric Cardiology, May 16 - 19, 2007, Warsaw.
- S. Minisini, F. Gervaso, M. Prosi, P. Zunino, F. Migliavacca, L. Formaggia, G. Dubini
Computational Models of Drug Eluting Stents in a Artherosclerotic Coronary Artery.,
EBR 2006, May 2006, Marseille.
Teaching Activities
Politecnico di Milano
- a.y. '07-'08 summer semester: teacher of the course
Metodi numerici per l'ingegneria Biomedica e Nucleare, Polimi
- a.y. '07-'08 winter semester: teacher of the course
Metodi numerici per le Equazioni alle Derivate Parziali (Ing. Mat.), Polimi
- a.y. '06-'07, '07-'08 winter semester: teacher for the course
Metodi Analitici e Numerici per l'Ingegneria Aerospaziale, Polimi
- a.y. '04-'05, '05-'06, '06-'07 summer semester: assistant for the course
Analisi Numerica (Ing. Mat.), Polimi, Prof. A. Quarteroni.
Ecole Polytechnique Federale de Lausanne
- a.y. '02-'03, summer semester: assistant for the course Analyse Numérique,
EPFL, Prof. A. Quarteroni.
- a.y. '02-'03, winter semester: assistant for the course Mathematical Modelling ofthe Cardiovascular System,
EPFL, Prof. A. Quarteroni.
- a.y. '01-'02, summer semester: assistant for the course Analyse Numérique,
EPFL, Dr. L. Formaggia.
- a.y. '01-'02, winter semester: assistant for the course Analyse III,
EPFL, Prof. Y.Biollay.
- a.y. '00-'01, summer semester: assistant for the course Analyse Numérique,
EPFL, Dr. L. Formaggia.
- a.y. '00-'01, winter semester: assistant for the course Analyse I, EPFL, Prof. Y.Biollay.
- a.y. '99-'00 summer semester: assistant for the course Analyse Numérique,
EPFL, Prof. A. Quarteroni.
Work Experience and Collaborations
- Summer '99-April 2005, Lausanne: collaboration with Debiotech S.A
- October '02-present, Lausanne-Graz-Milan: scientific investigator
in the Haemodel
Project.
- Febuary '03, Graz: collaboration with the
Biofluid Mechanics Research Group, Graz University of Technology.
- Subject: Mathematical and numerical models for transfer of low density lipoproteins through the arterial walls.
- December'02, Tokyo: collaboration with Terumo Corporation

- Subject: development of computer software for the numerical simulation of peritoneal dialysis.
- December '02, Graz: collaboration with the
Biofluid Mechanics Research Group, Graz University of Technology.
- Subject: mathematical modelling and numerical simulation of mass transfer in the vascular system.
- June '02-present, Lausanne and Ghent (Belgium): collaboration with
Ghent University Hospital
- Subject: clinical validation of numerical simulations of peritoneal dialysis.
- May '01, Graz (Austria): collaboration with the
Biofluid Mechanics Research Group, Graz University of Technology.
- Subject: mathematical modelling of mass transfer through the arterial walls.
Links